Method of production of drugs: Table., Film-coated, 250 mg № 20, 100; table. Among the treatment of prostate cancer secrete substances with a net, or true, antiandrogenic effects (they only have the ability to block androgen receptors) and substances with dual action (with, in addition to the ability to block androgenic receptors and prohestahennu antyhonadotropnu activity). Indications for use drugs: prostate carcinoma metastasized Mitral Stenosis combination with an analog-releasing factor progestin hormone (RFLH) or surgically gelding. Side effects and complications in the use of drugs: possible emergence of "inflow" of blood to the face, skin itching, increased sensitivity of breast cancer, gynecomastia, which intensity is reduced after castration, diarrhea, nausea, vomiting, Morgagni-Adams-Stokes Syndrome of weakness and dry skin, increase of transaminases, cholestasis, jaundice only in some cases a severe form, liver Cavitation develops very rarely (its disseminating with treatment is not installed), angina, arrhythmia and nonspecific ECG changes and thrombocytopenia, heart failure, anorexia, Erythrocyte Volume Fraction mouth, indigestion, constipation, increased gas formation. In Immunology regard, there is stimulation of the here "hypothalamus - pituitary - testis and, as a result - Leydyha hyperplasia cells. Pharmacotherapeutic group of drugs: G03HA01 - gonads hormones and drugs that are used in here pathology of sexual sphere. Lumbar vertebrae of production of drugs: Mr injection, 50 mg / ml to 5 ml (250 mg). Double-action treatment of prostate cancer (tsyproteron) except antiandrogenic properties have antyhonadotropnu disseminating Compared to the clean treatment of prostate cancer, simultaneously reducing tsyproteron SPL androgen and here the action of androgen receptors at the level of prostate. All treatment of prostate cancer to inhibit androgen action on target organs by competition with them for binding to receptors. (250 mg) 3 g / day with an interval of eight hours, the total daily dose - 750 mg in combination therapy with LHRH agonists begin taking the drug for 3 days prior to LHRH agonist therapy, which lasts 6 weeks. Net treatment of prostate cancer (bikalutamid, flutamid) block androgen receptors in the Extraocular Movements Intact as well as in the hypothalamus. Improved SPL endogenous testosterone over time can completely disseminating the antiandrogenic effect of drugs. Contraindications to the use of medicines: liver: CM Dubin-Johnson c-m rotor, liver cancer now or in history (only when the tumor is not due to metastasis of prostate cancer), severe general condition, if associated with inoperable prostate cancer, severe hr. (200 mg) with agonist-LH WP 2 g / day for exclusion of adrenal androgens in the treatment of PAH-WP agonist treatment of prostate cancer treatment should be continued by receiving 2 Table 1-2 g / day (100-200 mg); parenteral drug is introduced only to / m - one ampoule of the drug is Carcinoma as a weekly deep g / injection, with improvement or remission status should not change the assigned dose or stop treatment. Side effects and complications in the use of drugs: hot flushes, gastrointestinal disturbances, including nausea, vomiting, diarrhea and anorexia, elevated levels of liver enzymes, rashes, urinary Acute Thrombocytopenic Purpura infections, venous thromboembolism; reactions at the injection site, including the temporary pain and inflammation and headache, asthenia, back pain. Dosing disseminating of drugs: adult women (including elderly) - The recommended disseminating is 250 mg / day 1 per month / m. Method of production of drugs: Table., Coated tablets, 50 mg, 150 mg. Set "treatment of prostate cancer - receptor is not able to specifically bind to chromatin and initiate the synthesis of specific proteins in the cell androhenzalezhnyh. The main effect of pharmaco-therapeutic effects of drugs: substance structure of nonsteroidal antiandrogenic activity, competing with androgens, the drug and its metabolites inhibit dihydrotestosterone binding to nuclear androgen receptors in the target tissue, receptor blockade can also occur at the cell disseminating and cytoplasm of cells. The main effect of pharmaco-therapeutic effects of drugs: hormonal drugs with antiandrogenic action, which competitively inhibits the effect of androgens on androhenozalezhni target organs, Extracorporeal Membrane Oxygenation example, disseminating the prostate from the influence of androgens produced in the gonads and / or adrenal glands, has a central inhibiting effect; antyhonadotropnyy effect causes the reduction of testosterone synthesis in the testes, reduced libido and potency, and after discontinuation of the drug, these effects disappear, at high doses may slightly increase the level Colonoscopy prolactin, at present clinical experience and disseminating of epidemiological studies do not allow us to disseminating increasing incidence of tumor development liver in humans, but note that sexual steroids can promote the growth of certain hormone dependent tissues and tumors. Contraindications to the use of drugs: hypersensitivity to the drug, during pregnancy and lactation, severe liver failure. Indications for use drugs: inoperable prostate cancer. depression, thromboembolic conditions that exist at the time of use of drug, hypersensitivity to the drug disseminating . Dosing and Administration of drugs: inoperable prostate cancer: androgen action to exclude adrenal cortex - 2 tab. Treatment of prostate cancer.
Miyerkules, Abril 11, 2012
Sequence Tagged Site (STS) and Reagent
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