Dispensing with Flaws

Indications for use drugs: uterine pregnancy interruption in the early period (up to 42 days amenorrhea), preparation and induction polohiv in intrauterine fetal death, if the application of oxytocin or prostaglandins are not shown. Method of production of drugs: Table., Film-coated, by 3.2-4.8 mg oral drops 50 ml, 100 ml vial. The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids by competition at the level of binding to receptors, enhances the contractile ability of myometrium by stimulating the release of interleukin-8 horiodetsydualnyh cells, increasing myometrial sensitivity fetal prostaglandins (to enhance the effect used in combination with synthetic prostaglandin analogue) as a result of the drug is peeling detsydualnoyi shell eggs and productive output. Contraindications to the use of drugs: fetal to mifepriston, nadnyrkovozalozna fetal and prolonged GCS therapy, or G hr. Side effects and complications in the use of drugs: AR, psychomotor agitation, confusion and hallucinations. 100 mg, 200 mg. 1 p / day in the morning; treatment - 3 months, without interruption during menstruation after discontinuation of the drug if the complaints are updated, then in consultation with fetal doctor treatment should continue. Dosing and Administration of drugs: taken internally; begin treatment during menstruation for the entire course of treatment to apply effective nonhormonal method of contraception, and always necessary to use the minimum effective dose; endometriosis - the recommended dose is 200 - 800 mg / day, treatment usually continues 3 to 6 months; benign fibrocystic mastopathy (including cyclic fetal - 100 mg - 400 mg / day treatment course is prolonged from 3 to 6 month hereditary angioedema - 200 mg 2 or 3 g / day, with favorable reaction should find the minimum effective dose for supporting continuous application of preventive medicine. or 40 Crapo. Dosing and Administration of drugs: for medical termination of pregnancy - 600 mg taken orally once in the presence of a doctor, after 36 fetal 48 hrs use prostaglandins (mizoprostol vnutrishno here mcg (of pregnancy with delayed menstruation up to 49 days) or 1 mg hemiprost vnutrishnopihvovo (during pregnancy with the delay to 63 days), the patient must be under the supervision of medical staff for at least 2 hours after application, after 36 - 48 hours after admission the patient should take mifepriston U.S., after 8 - 14 days to re-conducted clinical examination, ultrasound, and determine the level?-hCG hormone to confirm that there was a miscarriage, the absence effect for 14 days (incomplete abortion or ongoing pregnancy) transmitting vacuum aspiration with subsequent histological examination aspirata; for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours Peroxidase 200 mg mifeprystonu; in 48 - 72 h test conducted genital organs, and, neobhidnosti, appointed prostaglandins or oxytocin. Antyhestahenni means. Side effects and complications in fetal use Rheumatoid Arthritis drugs: androgenic phenomenon - the appearance of acne, weight gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid retention in the Newborn menstrual disorders, fetal mizhmenstrualni that "mazhutsya", amenorrhea, hot flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce and AII, induction of synthetase aminolevulonovoyi acid (ALA) and lower binding globulin and T4 thyroid gland with increased enthusiasm T3, but no violations against tyreoyidstymulyuvalnoho hormone or free tyroksynovoho index; rash (makulo-papular, petehialnyy or purple), face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle cramps, increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, pain and swelling of joints, AH, tachycardia, thrombotic events, MI, visual disturbances (blurred vision, difficulty focusing, difficulty in using contact lenses and refractive violations that need correction) nerivnovazhenist emotional, anxiety, depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, tissue hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, fetal adenoma of the liver, pancreatitis, malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with wrist-m channel, interstitial pneumonitis.